Solid phase strain promoted "click" modification of DNA via [3+2]-nitrile oxide-cyclooctyne cycloadditions.
نویسندگان
چکیده
Rapid, catalyst free, solid phase modification of DNA by strain promoted cyclooctyne-nitrile oxide click chemistry is reported; the reaction is characterised by mild conditions, occurring in an aqueous environment under atmospheric conditions at room temperature and is complete in 10 minutes.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 47 9 شماره
صفحات -
تاریخ انتشار 2011